|
KMID : 0359920060250061007
|
|
Korean Journal of Nephrology
2006 Volume.25 No. 6 p.1007 ~ p.1011
|
|
|
Reinduction of Hyponatremia by Vasopressin to Prevent Osmotic Demyelinating Syndrome
|
|
Jang Ji-Sun
Kim Sung-Eun
Lee Sang-Kyu
Kim Hyeon-Kyu
Kim Doo-Man
Kim Su-Jin
Lee Young-Ki
Park Tae-Jin
Yoon Jong-Woo
Oh Ji-Eun
|
|
|
Abstract
|
|
|
|
Rapid correction of chronic hyponatremia can be associated with osmotic demyelinating syndrome leading to irreversible rain injury. Therefore, the primary efforts must be focused on maintaining appropriate correction rate (<10-15 mEq/L/24hr). But overcorrection may occur unpredictably in various circumstances. However, several reports showed that rapid relowering of the serum sodium level prevents osmotic demyelinating syndrome and reduces neurological injury. We report two cases of overcorrected chronic hyponatremia. After overshooting, we considered the risk of osmotic demyelinating syndrome and injected vasopressin to patients. The serum sodium concentrations were relowered immediately with no neurological deficit. There was no significant side effect of vasopressin. (Korean J Nephrol 2006; 25(6):1007-1011)
|
|
|
KEYWORD
|
|
|
Hyponatremia, Demyelination, Vasopressin
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|